Actiflash是一种小的类固醇配体,在光诱导下激活工程蛋白。它可用于在活细胞培养物和动物中精确控制蛋白质活性至单细胞水平。
How does it work?Actiflash is a tamoxifen-like caged-inducer called cyclofen. Upon UV-light illumination, optical-induced uncaging of Actiflash quickly releases proteins fused to the modified estrogen receptor ligand-binding domains ERT2. This allows them to translocate into the nucleus, activate transcription (using Gal4-UAS system) or induce recombination (using the Cre-lox one).
The protein expression can thus be simply controlled in time and space thanks to UV-light!
产品订购:
产品名称 |
货号 |
规格 |
光诱导蛋白激活剂 Actiflash |
LJU-CIN-5 |
5mg |
光诱导蛋白激活剂 Actiflash |
LJU-CIN-50 |
50mg |